The Arthur P. Noyes Research Foundation
Science for the benefit of people living with schizophrenia
2006 Conference

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Copyright ©2005
by Sara Steele,
All Rights Reserved
ARTHUR P. NOYES SCHIZOPHRENIA CONFERENCE
Thursday and Friday, September 22-23, 2005
Neither solely science nor solely spirit/psyche,

Neither pure cognition nor pure emotion,

Neither genome nor environment alone,

Neither neural connections nor community connections acting in isolation,

Neither natural molecule nor human-made medication independently,

but rather

the whole picture, the interaction of all these elements,
as they nurture or diminish
the wholeness of a human life lived with schizophrenia.

Toward Wholeness
TOWARD WHOLENESS, The 19th Annual Arthur P. Noyes Schizophrenia Conference
intends to contribute to movement in two directions:

• away from false dichotomies and toward a synthesis which recognizes the complexity of the disease, and the complexity of individuals with the disease,

• toward the inclusion of scientific breakthroughs beyond the field of schizophrenia in our vision of the future of research and treatment.

The participants in the Sept. 22 pre-conference conversation and the Sept. 23 conference day: Aaron Beck, Wayne Fenton, Fred Frese, Daniel Gottlieb, William Greenough, John Nash, Candace Pert, Ming Tsuang are leaders in their individual fields of inquiry, and share a history of bridging and integrating divergent disciplines to discover new pathways. We hope you will join us.

Richard C. Josiassen, Ph.D., Chief Scientific Officer

TOWARD WHOLENESS
A Community Forum: On Cognition
Thursday, September 22, 7:00 PM
at the Chambers-Wylie Cathedral, 319-327 S. Broad Street, across from the Kimmel Center.
A Conversation with Aaron Beck and John Nash
Aaron T. Beck, M.D., University Professor of Psychiatry at the University of Pennsylvania School of Medicine, is one of the “founding fathers” of the cognitive revolution in psychotherapy and is considered the most influential psychotherapist in the world today. He has also been listed as one of the ten persons in history with the greatest influence on American psychiatry. He is the author or co-author of over 500 publications, including 17 books. His cognitive therapy represents a major advance in the understanding and treatment of psychological problems and has been shown to be an effective adjunct to the treatment of schizophrenia in numerous studies.
John Forbes Nash, Ph.D. was 66 years old when he won the Nobel Prize (in Economics) for his pioneering work in game theory, and yet, for much of his adult life he exhibited the symptoms of paranoid schizophrenia. He began graduate study at Princeton in 1948 when he was 20. He obtained his doctorate with a 27-page dissertation on game theory - and drew the attention of theoretical economists from around the world. He went on to MIT and made additional contributions to mathematical research while he was on the faculty there. Then, for 25 years, after a few short intermissions of rationality, his life was ruled by delusions. In the mid-1980s, he began to learn to control delusional tendencies and regained rationality of mind. General interest in his life story led to the production of the academy-award winning film A Beautiful Mind, which took its name from the title of a book written about him (as an unauthorized biography). Today Nash holds a research position at Princeton University. His work stands as the basis for much of modern economics and game theory and is of notable interest in other mathematical fields also.
Friday, September 23, 8:00 AM to 4PM
at The Pennsylvania Convention Center, 12th and Arch Streets in Philadelphia
The theme of this year’s conference, TOWARD WHOLENESS, touches on the commitment of Arthur P. Noyes, M.D. to "…the science that mattered in alleviating suffering," and to using the ever-evolving methods of both social and biological science to advance our knowledge of schizophrenia. We intend this conference to be a movement toward wholeness on three fronts:

First and foremost, toward an understanding of the treatments and the potentials which contribute to wholeness of life for the individual diagnosed with schizophrenia.

Second, towards a more complete view of the richness of factors which move individuals toward wholeness, including new discoveries in peptides, brain plasticity, and genetically individualized pharmacotherapy on the "chemical" side of the equation to cognitive therapy advances and an increasing focus on the impact of the community on the individual on the non-chemical front.

Finally, toward expanding our view of what schizophrenia research can be by including the whole of the remarkable breakthroughs occurring in neuroscience, genomic mapping, and molecular biology as we chart the future course of research.
Faculty
Daniel Gottlieb, Ph.D. began his practice as a psychologist and family therapist in 1969. As a young psychologist, gaining respect from his peers and raising two young daughters, life seemed perfect. Then in 1979, Gottlieb was in a near fatal automobile accident, which left him paralyzed from the chest down. Over the ensuing years, he faced depression, divorce and multiple additional losses. Throughout all, his resilience allowed him to maintain his career. Now, from his physical perspective of a wheelchair, he gains and shares unusual insight into what it means to the human. Since 1985 Dan Gottlieb has hosted "Voices in the Family", an award-winning mental health call-in radio show aired at WHYY 90.9 FM public radio. He also authors a bi-monthly column for the Philadelphia Inquirer entitled: "On Healing".
Fred Frese, Ph.D. was first diagnosed with paranoid schizophrenia while serving in the U.S. Marine Corps in 1965. During the following decade, he was involuntarily hospitalized for this condition, and, moving forward with his life and the disease, earned masters and doctoral degrees in psychology from Ohio University. He is currently a faculty member in the psychiatry departments at both Case Western Reserve University and the Northeastern Ohio Universities College of Medicine. He has published numerous articles and several book chapters concerning recovery from mental illness. He recently edited the volume, The Role of Organized Psychology in Treatment of the Seriously Mentally Ill. Although his court commitment occurred over 35 years ago, Fred has yet to receive official notification that he has been restored to sanity. He is sure this must be an oversight
Candace Pert, Ph.D. is a leading researcher in neuropeptide and receptor pharmacology. Her patents include applications of neuropeptides to diseases as diverse as psoriasis, Alzheimer’s, chronic fatigue syndrome, stroke, head trauma, and the current focus of much of her work – AIDS. Schizophrenia, and the evidence suggesting it is a neuro-inflammatory disease, are an early and continuing passion. A research professor in the Department of Physiology and Biophysics at Georgetown University Medical School, she is best known for her discovery of opiate receptors in the brain. She was a featured expert in the highly acclaimed Bill Moyers PBS series “Healing and the Mind” and “What the Bleep Do We Know?” and is the author of Molecules of Emotion, Why You Feel the Way You Feel.
William T. Greenough, Ph.D. is a professor in the University of Illinois departments of Psychology, Psychiatry, and Cell and Structural Biology, and a full-time faculty member in the Beckman Institute NeuroTech Group. His fields of research interest are mechanisms of brain-behavioral development, neural mechanisms of learning and memory; restoration and repair of the developmentally damaged nervous system, plasticity of non-neuronal cells and systems of the brain. One of his areas of interest is the role of plasticity in schizophrenia.
Ming Tsuang, M.D., Ph.D., D.Sc., is currently appointed University Professor, University of California; Distinguished Professor of Psychiatry, and Director, Institute of Behavioral Genomics with the Department of Psychiatry at the University of California, San Diego. Previously, he was the Stanley Cobb Professor of Psychiatry at the Harvard Medical School and director of the Harvard Institute of Psychiatric Epidemiology and Genetics. He is recognized worldwide for his research in schizophrenia, manic-depressive illness, and substance abuse, which has included a 40-year longitudinal outcome and family study of schizophrenia and manic depression. Much of his work has focused on the interaction between genetic and environmental risk factors for severe mental disorders. He has received numerous major awards.
Wayne S. Fenton, M.D., is Director, Division of Adult Translational Research and Treatment Development, National Institute of Mental Health, Bethesda, Maryland. Dr. Fenton’s research has focused on the integration of biological, psychological and policy initiatives for the treatment of severe mental illness. He has conducted clinical trials of pharmacological and psychosocial interventions for schizophrenia and other serious mental illnesses, is the author of many publications related to this research, and is the recipient of numerous awards. At NIMH, where he also serves as Associate Director for Clinical Affairs, Dr. Fenton has developed model programs for academic-industry-regulatory collaborations in support of treatment development for serious mental illness including the MATRICS and TURNS programs.

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